These results show that the frontal orienting fields are necessary for making decisions based on accumulated evidence, but further experiments suggested that the accumulation process itself seems to happen elsewhere in the brain.
Under balanced reward conditions, the two accumulators compete on equal footing (the other accumulator is not shown), and the outcome of the decision process is therefore determined by the relative strength of the motion input to the two LIP accumulators plus stochastic variability in the sensory evidence and in the accumulation process itself.
Factors influencing the bioaccumulation of trace elements in macrofungi and the biological importance of the accumulation process itself are poorly understood.
Alternatively, in our model the adaptive accumulation process can be suspended, at least temporarily, not by an extrinsically imposed decision rule like an absorbing decision boundary but rather by the non-linear dynamics of the accumulation process itself.
(c) We next considered the possibility that the FOF plays a role in the accumulation process itself, and quantified biases in accumulation through an 'accumulation shift' that shifts the value of the accumulator, a, at the end of the stimulus (see Figure 5C, equivalent to Þ in Figure 2 figure supplement 1).
In addition, the results show that the rate of mutation accumulation itself can be lower in a subdivided population than in an undivided population, despite the disadvantage of population subdivision due to enhanced drift.
Our data point to a physiological response to the accumulation of NaCl itself rather than to an osmotic shock response.
In such studies tissue lipid accumulation is usually appreciated by measuring triglycerides (TG) content although recent studies clearly show that deleterious effects are not due to the accumulation of TG itself [ 5] but to other lipid metabolites such as palmitate, diacylglycerols and ceramide [ 6- 8].
Combining both protein and RNA level of HFR1 that we detected, it is possible that the accumulation of HFR1 protein itself provides a negative feedback signal to its transcription, and this feedback signal is attenuated in cry1 mutants due to a significantly reduced amount of HFR1 protein.
If the accumulation of DNA damage itself is the bigger lifespan reducing challenge in xpa-1, we would expect nth-1 xpa-1to be more severely affected.
