According to this model, there is a slight increase in MMSE before the accelerated decrease.
We can hypothesize that the accelerated decrease of VEGF and PEDF genes expression at the mRNA level in OXYS rats is due to early RPE dysfunction because both of these genes are primarily expressed in RPE cells.
Secondly, fossil carbon introduced into the atmosphere has a lower δ13C than background carbon, thus inducing an accelerating decrease in δ13C in the biosphere (the Suess effect, [28]).
Clearly, there is a trend of an accelerating decrease in HINT score, especially for resolutions worse than 3.0 – 3.5 Å, indicating that, just as we hypothesized, these models indeed have poorer quality hydropathic interaction networks.
One possible confounder may have been the introduction of heptavalent pneumococcal vaccine in late 2005: however, any change before then cannot be attributed to the vaccine and, in the post-introduction period, there was no obviously accelerated decrease in the incidence of AOM.
The primary cause of the increased fracture risk appears to be an accelerated decrease in bone mineral density (BMD) resulting from the loss of estrogenic signaling that occurs with most treatments for breast cancer, including aromatase inhibitors.
Furthermore, inhibition of protein translation by anisomycin in NALM-6 cells led to an accelerated decrease in c-Myc expression in the presence of JQ1.
Chronic smoking related changes in pulmonary function are reflected as accelerated decrease in FEV1 although histologic changes occur in the peripheral bronchi earlier.
Mixed culture derived from SOD1G85R embryos showed an accelerated decrease of motor neurons compared with that of the wild-type one and CysC treatment markedly improved the viability of SOD1G85R motor neurons.
Locomotor activity of Aβ1 42 flies shows an accelerated decrease compared with Aβ1 40 or control flies (Fig. 1B).
