Sentence examples for the absence of efficacious from inspiring English sources

For example, after the initial training in theoretical considerations of RNA secondary structure and function, the students concluded primary literature searches on the role of RNA secondary structure in viral replication and identified the YF virus as a pathogen of interest based on the biomedical needs such as the absence of efficacious vaccines.

Although sorafenib was not effective as a single agent in advanced melanoma (Eisen et al, 2006), it was thought worthwhile to explore the utility of sorafenib in combination with chemotherapeutic agents in the treatment of patients with advanced disease, especially given the absence of efficacious treatment options.

Highly pathogenic viruses are endemic in developing countries where their impact on public health is especially important in light of the absence of efficacious treatments and vaccines 1. Occasionally, they can be brought into the developed world by travellers and could be misused for bioterrorism.

Armed with so little information about intrinsic vulnerability, the physician not only is unable to predict whether a patient will develop TD but, in the absence of efficacious treatments, also can expect that many of those for whom haloperidol is prescribed will be left with a permanently disfiguring condition.

Given the absence of an efficacious HIV vaccine and the impracticality and unethicality of eliminating animal reservoirs, global eradication of HIV is highly implausible.

Dengue incidence continues to increase globally and, in the absence of an efficacious vaccine, prevention strategies are limited to vector control.

2 The study does not evaluate interventions for stomach cancer because of the absence of known efficacious interventions.

Most of the centres were located in Eastern Europe, Asia, South America and Africa and likely were not yet skilled in or accustomed in the use of TKIs and possibly were forced to enter patients into clinical studies in the absence of other efficacious treatment options, mainly for economic reasons (Srinivas, 2013).

In not one of those cases did the Court "questio[n], in the absence of a more efficacious sanction, the continued application of the [exclusionary] rule to suppress evidence from the State's case" in a criminal trial.

While abandonment of both Mapp and Kaufman has at times been advocated, no Justice has intimated that Weeks should also be overruled, at least in the absence of suitable and efficacious substitute remedies.

In the absence of EBOV-specific treatments, efficacious disinfectant and antiseptic products are useful to help prevent the spread of infection [ 6].