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Along with other findings on the abnormal function of the amygdala, research is beginning to narrow the search for the brain basis of autism".
Other symptoms such as hypertension, Cushing syndrome or electrolyte imbalance, which might relate to the abnormal function of the adrenal gland, were not observed in the cohort.
Thus, the abnormal function of the MuSK mutants can not be explained on the basis of an impaired interaction between agrin and MuSK through the co-receptor Lrp4.
These findings could be key for the understanding of the abnormal function of the human placenta in states of hypoxia such as preeclampsia.
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The abnormal function of these ion channels can alter the membrane potential.
Mutations in these genes could cause the abnormal function of these proteins and could influence mineral concentrations.
Several human AQP genes have been cloned and an increasing number of disturbances have been found associated to the abnormal function of these proteins [ 11].
A potential explanation for these results is the abnormal functioning of the frontostriatal circuitry.
This is not surprising, considering that in SZ many fundamental psychotic features, including the lack of awareness, impaired control of actions, poor attention, increased reaction times, etc., are associated with the abnormal functioning of the superior parietal cortex [83], [84].
These results indicated that the mutant phenotype should be caused by the abnormal function of REL2 protein.
This technology is an intracellular application of gene-engineered antibodies, aimed at ablating the abnormal function of intracellular molecules.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com