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A possible explanation is that the functional connectivity would be the first step leading to increased activation in a region that would activate as a compensatory mechanism.
The increase of miR-34a expression in HPV infected cells is probably explained by the activation of cellular repair mechanisms after viral infection that would activate p53 pathways and therefore induce miR-34a expression.
Inspection of the active site of GLI does not reveal either a general base that would activate the 4-OH group of the δ-lactone for intramolecular attack on the lactone carbonyl group or a nucleophile that would allow the formation of an acyl enzyme intermediate that would partition between the δ- and γ-lactones.
He should recognize that the "invisible hand" in India and Pakistan could press a button that would activate a nuclear holocaust.
Homeowners should not use a cordless phone to make the call, he said, since that would activate the base unit inside the house.
Should one encounter a bear, however, the most important thing, Mr. Rezendes said, is to not run, a response that would activate its predatory instincts.
Similar(23)
Alternatively, the CaMKIIβ response may indicate failure of calcium homeostasis, a factor that would also activate proteolytic activities such as calpains and caspases [ 50, 51].
A deficit of that size would activate a law that forces a state fiscal takeover of the county in the event of an imbalance of at least 1percentt.
A telephone survey demonstrated that 89% of respondents stated that they would activate EMS with a suspected cardiac event, but only 23% actually did use the service [4].
Far from being a scapegoat, Mr. Conille chose to be the sacrificial lamb that would both activate and perturb the cycle of power that Haiti has suffered throughout its history.
Indeed, antennal amputation abolished grooming at temperatures that would normally activate dTrpA1 and elicit antennal grooming.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com