As the referee correctly points out, it will be intriguing in the future to study quantitatively in more details the interplay between ring positioning, that we elucidate here, and the detailed cell shape.
The development of cardiac fibrofatty scarring is known to be a principal pathological process associated with ventricular arrhythmias, and it is vital that we elucidate the role of various cell populations involved in the disease if targeted therapeutics are to be developed.
Once we elucidated that Hsp90α is a critical chaperone of PKCγ and regulates its stabilization and membrane translocation, we asked whether PKCγ can directly phosphorylate Hsp90α.
Taken together, we elucidated that ceRNA regulation is a complex and sophisticated mechanism in vivo, thus difficult to be observed under some cellular conditions.
In this study, we elucidated themes that contribute to or inhibit overall HRQOL rather than suggesting that these themes constitute the breadth and comprehensiveness of that quality per se.
We elucidated that the effects of step-up shear can be divided into two regions: below and above a critical shear rate, ˙γc,SD.
We elucidated that the dynamic friction force in single layer tissue presented as a product of the pressure applied to the needle by the tissue, the dynamic friction coefficient, and the area of the needle touching the tissue [10].
Finally, we elucidated that future trend of research on ecological assets would pay more attention to the internal mechanism of changes of ecological assets, determination of the bearing capacity of the ecological environment by such changes, and discovery of accumulation of ecological assets for a stable and sustainable development of the ecosystem, and for harmony between humans and environment.
In addition, we elucidated that Yokukansan and Senkyu inhibited the activation of caspase-4 observed under ER stress (Figure 5).
