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It thus appears that very abundant tester-specific transcripts escape normalisation, whereas very abundant transcripts expressed in both tester and driver escape both subtraction and normalisation.
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To check for genes that are potentially subject to post-transcriptional regulation, we selected genes that were very abundant in the mRNA-Seq data and rare in the proteome-map (coloured green in Figure 6) or the inverse (coloured red).
If amino acids were so abundant, that they would be a convenient source of energy, then why amino acids that are very abundant in the Miller experiment are not represented in the genetic code (e.g. sarcosine, N-metylalanine, etc., Miller and Urey 1959 Science 130 245)?
The "general meeting" is a term that is very abundant in Hollywood.
We also found that METH-mediated activation of ER stress-dependent events is dependent, in part, on the stimulation of DA D1 receptors that are very abundant in the rat striatum [57].
Perchloric acid treatment, commonly used for inositol polyphosphate extraction of yeast cells [20], mainly extracts inorganic polyphosphates that are very abundant in this organism [26] and are negatively stained by DAPI [22].
ThMP is probably transported through the choroid plexus by the reduced folate transporter (SLC19A1), that is very abundant in the apical (CSF) side of the choroid plexus [65] and able to transport ThMP (but not thiamine) in addition to reduced folate [66].
Apparently the genomes of T. grandiflorum and H. balaensis are significantly deficient in many LTR retrotransposons families that are very abundant in T. cacao.
Sequencing 1600 clones from one of the libraries confirmed and extended our results to endogenous transcripts and demonstrated that some very abundant transcripts common to tester and driver escaped subtraction.
This implies that for very abundant reads (the most abundant in our dataset has close to 107 copies) every single 1-SNP variant is present in significant quantities, and most of the 9L (L-1)/2 possible 2-SNP variants should also be present.
These ecological consequences of phenotypic variation/change are expected to be particularly important in species with large per capita ecological roles (e.g., keystone species and foundation species) or that are very abundant or rapidly evolving (e.g., some pathogens or pests).
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