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When we referred to clinical relevance, we meant to suggest that this timescale could be relevant in other, less acute, clinical situations where long-term health problems are involved.
It is perhaps noteworthy that this timescale for association is of similar magnitude to that for the subunit exchange of αB-crystallin (22), and may indicate that the αB-crystallin subunits are the active chaperone species.
Uhlmann et al. [ 1975] suggest that this timescale is related to the melt viscosity η, the melt-vapor interfacial tension γ, and the initial radius of the sintering particles (1) [18] Values of τ s correspond to the timescale over which the dominant process acts.
Similar(57)
Thus, the correlations in endogenous activity across ARC neurons differ significantly from the hypersynchronous correlations at this timescale that likely occur across ARC neurons during periodic, 1-s duration photostimulation often employed in vivo.
Key biological processes that occur on this timescale include enzymatic catalysis, ligand binding, and local folding.
Our inability to measure, because of the intrinsic methodological difficulties, the various gene-gene and gene-environment interactions and the way they affect chromatin and DNA means that over this timescale our disease risk assessments based on DNA sequence information will remain, in an important sense, incomplete.
Our results show that if diagnosis on this timescale is used for the prescription of antivirals for treatment or prophylaxis, their effectiveness is greatly diminished.
This timescale indicates that the efferent action in our experiments is unlikely to stem from the diffusion of Ca2+ from efferent synapses to the site of adaptation.
"The overall timetable of 2017 – we will deliver this in that timescale.
Cutting that sum within that timescale would be difficult and controversial, and could be made even harder by low inflation rates.
In an email apparently responding to Cabinet Office dissatisfaction with that timescale, a DIS expert wrote: "We refuse to budge on timelines – two years min…." The documents show that the Cabinet Office continued to question this timescale.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com