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The investigation demonstrated an approach to creating fluid power models for this application that can be used in simulation, but also indicated that substantial effort is required in the process.
There is no doubt that substantial effort will be made to improve personalized therapy.
Our findings suggest that substantial effort may be warranted into developing preventive interventions, as the cost of providing care homes is very high.
Study results show that substantial effort is needed to accelerate rates of progress, by a factor of 2 in most study countries, suggesting a need for strategic planning, including resource allocation, at the global and country levels.
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Our goals are to highlight that the status quo regarding the introduction of new device technologies is not acceptable, that substantial efforts are needed by all stakeholders to invest in systems of careful evaluation and to promote controlled and evidence based introduction of device innovations.
"This is not the proper time to stop or chill that very substantial effort that is being made," Mr. Purcell said.
Despite that substantial research efforts have been made on mechanical characterization of various one-dimensional (1-D) nanomaterials under quasi-static loading, very few works have been done so far on the challenging fatigue testing of individual 1-D nanostructures, in particular for their high-cycle fatigue behavior.
This is an area that requires substantial efforts from biologists and clinicians, statistical geneticists, bioinformaticians, and epidemiologists.
Significant barriers to this process of translation exist that will require substantial effort and resources to overcome.
A geographic area that has had substantial effort to compile a reference library is the subarctic region of Churchill, MB, Canada.
In the early days, it's important to focus on the "quick wins" — the immediate points of value that can be realized without substantial effort.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com