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HSPs are molecular chaperones that specifically prevent irreversible protein aggregation (Waters 2013).
As an additional safeguard against reversion, mutations that specifically prevent transmission may also be sought (e.g., Kim et al. 2011; Hanley et al. 2003).
Several mutations that specifically prevent the formation of Anneaux were also selected [ 19].
To this end, we developed novel mutagenesis procedures permitting the recovery of mutations that specifically prevent Secteur development.
We propose that future studies should focus on defining the pathways and mechanisms that specifically prevent or interfere with Dnmt3L-histone H3 interaction.
Current treatments are largely palliative and new therapies that specifically prevent the spread of breast cancer to bone are urgently required.
Similar(52)
As he put it, "[It's] not that social media replaces or reduces the need for human interaction, but when you're forced into a situation that specifically prevents human interaction, social media becomes your best alternative".
Because of the similar properties of Anneaux and Secteurs, we decided to screen for more mutations that specifically prevent Secteur formation, to determine if s mutations (i.e., a mutation that specifically prevents the generation of σ) could be obtained.
To date, only one mutation that specifically prevents Secteur formation has been described [ 18, 19].
Structure-based studies have recently led to the development of small-molecular-weight compounds that can specifically prevent interaction of Rac1 and Rac2 with activating guanine nucleotide exchange factors [ 27, 48].
Hence, there is an urgent need to identify the biological drivers of metastasis in ES and to develop novel therapeutics that will specifically prevent or target metastases in these patients.
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