Sentence examples for that site directed from inspiring English sources

Secondly, it is revealed that site directed mutation can inhibit amyloid fibril formation.

That site directed Mr. Nir to Meetup.com, and on Feb. 5, he and 14 others gathered at an event in Manhattan.

Further, analysis of the production levels could confirm that site directed integration significantly reduces the variations of clonal expression levels.

Besides further validating our strategy of inhibiting iron release, these Tf mutants provide proof-of-principle that site-directed mutagenesis offers an alternative method for improving the drug carrier efficacy of Tf.

These results indicate that site-directed single monolayer immobilization affords almost the same number of surface exposed Mb active sites as the random multilayer immobilization strategy, though the latter contains a greater number of protein molecules on the electrode surface, as observed from the AFM data.

Another previous report from Kong and colleagues also showed that site-directed mutagenesis of Nrf2 at several MAPK consensus sites did not affect the transactivation activity of Nrf2, although these sites do not overlap with the sites characterized in our present study [35].

Our data support the view that site-directed phosphoablative mutagenesis of specific PSKR1 AL residues impairs PSKR1 kinase activity in vitro and that phosphorylation of these serine and threonine residues is likely to be required for growth signalling through PSKR1 in planta.

For the site directed mutagenesis we used the Quickchange Site Directed Mutagenesis Kit (NO. 200518, Stratagene).

The addition of the EcoR1 site create an amino acid change from V85 to E that was corrected by site directed mutagenesis using the following oligonucleotides: Sense-5'-GCTGTGTGCTTCGTATTCATGGCTGGGG and antisense-5'-CCCCAGCCATGAATACGAAGCACACAGC.

Mutation of the active site Ser221 to Ala resulted in a lack of labeling, confirming that the inhibitor is active site directed (ESI Fig. 14 †).

It has been demonstrated through site directed mutagenesis that very few amino acid changes are required to change the enzymatic function of a FAD2 gene.