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Given the earlier described connection between genetic interaction profile similarity and allele distance, perhaps actin alleles that similarly affect actin structure and function should cluster more closely with respect to their genetic interactions.
Unexpectedly, genes that similarly affect both sexes (e.g., lethal, visible, male, and female sterile) are relatively female biased (transcriptionally) compared with the genomic distribution (fig. 1, top panel; P < 2.2 × 10−16).
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Another gene that similarly affects both vegetative and inflorescence axillary meristem initiation in maize is barren stalk1 (Zm-ba1) (Ritter et al., 2002; Gallavotti et al., 2004).
Including this covariate ensures that no measurement artifact (e.g., changes in assay kits) or any confounder that similarly affects both male and female gestations will induce inferential errors in test.
Mariluz's struggle to fulfill her obligations to be the primary caregiver for her children in the absence of sufficient economic resources resulted in a conflict that similarly affected many women her local community and nation.
Today, such killings are a product of anti-Mexican xenophobia that similarly affects the whole Latino immigrant population, and not just Mexicans.
On one hand, it reduces the overall variability in protein measurement by cancelling out systematic variation that similarly affects target and normalizing proteins.
For each slice, data-driven 'regressors of no interest' were selected via principal component analysis (PCA) of all voxels within the not-spine mask to identify structured noise sources that would similarly affect the spinal cord and external (neck) regions.
For each slice, additional data-driven 'regressors of no interest' were selected via PCA of all functional voxels within the CSF mask (defined in step #7) to identify structured noise sources that would similarly affect gray matter and CSF.
For example, it is easier for a parent or teacher to gain access to a prescription drug to treat ADHD or depression than to obtain evidence-based strategies that might similarly affect behavior (e.g., Ridgway et al. 2003; Schilling et al. 2003; Larun et al. 2006).
Collectively, the present study identifies molecular steps of insulin signaling in the liver and in the muscle that are similarly affected by two conditions that extend life, CR in normal animals and deletion of the GH receptor, but are not altered by CR in GHRKO mice in which CR fails to increase insulin sensitivity and therefore longevity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com