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At present the most widely held view is that serous carcinoma arises directly from the transformation of the ovarian surface epithelium or its inclusion cysts through a "de novo" process (16,17).
High-penetrating swept-source optical coherence revealed that serous retinal detachments resolved accompanied with a decrease of the central choroidal thickness in both eyes Fig. 4 Findings 7 months after the steroid tapering therapy.
MAL, the most differentially expressed gene, was further validated at the protein level and found to be an independent predictor of poor survival in an unselected group of advanced serous cancers (P = 0.0004).These data suggest that serous ovarian cancers detected at an early stage generally have a favorable underlying biology similar to advanced-stage cases that are long-term survivors.
This sample composition reflected the fact that serous cancers are more likely to be identified at a late stage, while the reverse is true for endometrioid, clear cell and mucinous cancers.
Although it is widely believed that serous ovarian cancers arise from the ovarian surface epithelium and inclusion cysts formed when ovarian surface epithelium become trapped inside the ovary [9], a more recent hypothesis for the initiation of ovarian cancer suggests that precursor lesions exist in the fimbriated end of the fallopian tube epithelium [10].
Finally, this study indicates that serous cystadenocarcinomas may be suitable tumours for MAGE-1 peptide immunotherapy.
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Our findings indicate that the serous ovarian cancer derived cell lines OVCAR3 and CaOV3 are good models of serous ovarian cancer to identify potential biomarkers given the similarities we have observed with tumor cells isolated from ascites from a patient with serous ovarian cancer.
After exam grades and feedback have been posted to the course website, and the exams returned in discussion section, students who believe that a serous error in grading has occurred may appeal.
After aspiration of the contents in the cyst that was serous fluid with slightly turbid, the cyst wall was excised as extensively as possible (Fig. 2b).
Subsequent work suggested that only serous tumours may be so influenced (Jordan et al, 2007, 2008).
Our results show, that in serous EOC, an intense nucleolar expression of PELP1 can be observed.
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