Sentence examples for that reading frame from inspiring English sources

The finding that 98% of gene fusions generate transcripts that can be translated as in-frame protein products confirms that reading frame conservation is of great functional importance in oncogenic fusion proteins, since the expected frequency of compatible reading frames between two random exons (assuming equal frequencies of +1, +2 and +3 reading frames) is one third.

End regions of alignments were trimmed such that reading frame (i.e. amino acid sequence) was identical for 3 consecutive codons.

The sum of the individual π values for all synonymous sites was then divided by the total number of synonymous sites (Nei and Gojobori 1986) in a given open reading frame in the reference sequence in order to obtain the synonymous nucleotide diversity (πS) for that reading frame.

Similarly, the sum of the individual π values for all nonsynonymous sites was then divided by the total number of nonsynonymous sites in a given open reading frame in the reference sequence in order to obtain the nonsynonymous nucleotide diversity (πN) for that reading frame.

A custom Perl program performed a computational ORF detection, which was a search in each possible reading frame for an ATG start codon followed by a stop codon (TAA, TAG, or TGA) at a distance of 100 nt or greater, with no intervening start or stop codons in that reading frame.

Note that "reading frame preservation" here means that the changes in exon length caused by such events are multiples of 3. In sum, one surprising finding of this study is that the FRFP of complex ASEs is lower than that of CSEs.

DNA from a number of these clones was sequenced to verify that joining had taken place correctly and that reading frames had been preserved.

It is well known that reading frames for vertebrate ND4L and ND4 genes partly overlap and that mature mRNAs for these genes occur as a di-cistronic mRNA [ 4].

ExAlt-Frame makes predictions without using exon coordinates as input but is limited to predicting exons that maintain reading frame consistency with the rest of the known gene.

Partial sequences, sequences with insertions-deletions that caused reading frame shifts and sequences with premature stop codons were excluded from analysis as likely pseudogenes in the nucleotide analysis.

Also, the mean GC content is higher for motifs that retain reading frame, and this accords with a higher GC content within coding sequence than elsewhere.