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Many enzymes catalyse reactions that proceed through covalent acyl-enzyme (ester or thioester) intermediates1.
Ceria is an important component of catalysts for oxidation reactions that proceed through the Mars-van Krevelen mechanism, promoting activity.
Mr. Benno butchers his own pigs throughout the year, and spring lamb and venison in season, building degustation menus that proceed through various bits of anatomy.
Current attempts at mimicking the transition states (TSs) of glycosyl processing enzymes (GPEs) that proceed through TSs with a high degree of oxacarbenium ion formation suffer from a paucity of data about the conformations of such oxacarbenium ions.
Spermatogenesis is a complex process during which diploid spermatogonia divide mitotically to provide a population of spermatocytes that proceed through meiosis to haploid spermatids which differenciate into spermatozoa [1].
Aggregates then tighten into mounds that proceed through differentiation and morphogenesis as physiologically integrated multicellular organisms.
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The viral protein HIVgp41 is an attractive and validated drug target that proceeds through a sequence of conformational changes crucial for membrane fusion, which facilitates viral entry.
A manualized organizational intervention that includes the use of external organizational coaches was applied to create and support interagency change teams that proceeded through a four-step process over a planned intervention period of 12 months.
However, on the basis of an inability to identify a catalytic nucleophile in the complex with α-glucosyl-1,3-isofagomine, a neighboring group participation mechanism for GH99 was suggested that proceeded through a 1,2-anhydro sugar [ 48 ].
These pauses of intimacy give space to a love story that proceeds almost entirely through pretence.
It is known that the phosphoUb-mediated activation of Parkin proceeds with a Ub mutant that cannot proceed through E1/E2/E3 cascades, pointing toward an allosteric mechanism (Koyano et al, 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com