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In fact one finds that folding is guided by a milestone event which occurs rather rapidly reducing the conformational space that needs to be sampled.
Furthermore, appropriating the same transfer constants (amRNA, bprot) for all modelled variables is a simplification of the model which was done in an attempt to reduce the size of the parameter vector and hence the dimensionality of the parameter space that needs to be sampled.
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Here we converted the information to be processed in each condition to bits based on the average number of arrows that need to be sampled.
We estimate the computational load for the grouping search as a logarithmic function of the product of the grouping size and the expected number of groups that need to be sampled in order to obtain one that is congruent.
The range of the minimal number of newly infected treatment-naïve adults that need to be sampled to detect a 5% threshold ranges from 50 to 70 newly infected treatment-naïve adults [2], [3].
After considering the variation of the herd size and the positive cutoff, the simulations determined that the minimum number of cows that needed to be sampled to ensure a minimum sensitivity and specificity of 95%% was 20 animals.
In general, it is difficult to model an ideal protein design framework with the consideration of full backbone and side-chain flexibility, since there are usually a huge number of conformations that need to be sampled even for a small protein.
Suppose that a dataset needs to be sampled with N=400, C=2, δmin=0.025 and δmax=0.035.
Census estimates of the number of individuals per household in the municipality were used to determine the number of households that would need to be sampled to achieve the sample size.
Equally, the high number of birds that would need to be sampled to obtain a precise and accurate estimate of the 2 parameters is likely to reduce as R0 increases, however in a situation where R0 is unknown, caution should be taken.
These vertices are obvious sampling points, but their distance can be arbitrary, so that the edges need to be sampled.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com