Sentence examples for that mfn from inspiring English sources

It is possible that Mfn levels are kept constant by several different pathways including MUL1 and the PINK1/parkin pathway.

Moreover, in PARKIN−/− primary neurons, the modification of Mfn2 was not observed after CCCP treatment (Fig.  4C, compare lane 2 with lane 4), confirming that Mfn undergoes Parkin-dependent ubiquitylation in response to a decrease in ΔΨm.

Follow-up one-sample t-tests showed that MFN amplitude significantly differed from zero for both unfair and very unfair high offers on Fz (N = 18; unfair, 2.9 μV; very unfair, 4.2 μV, p <.05) and Cz (N = 18; unfair, 3.1 μV; very unfair, 3.7 μV, p <.005), but not for low offers and Pz (N = 16).

Alternatively, MUL1 may act via an intermediary that promotes Mfn ubiquitination and degradation.

On the contrary, our data suggest that normal Mfn expression is required for PINK1-mediated neuroprotection.

Visual inspection of the grand average difference wave forms indicated that the MFN was maximal at Fz around 400 ms after the presentation of the offer.

It is important to note that the MFn-3 diet was also fed as a control diet to all cats for 4 weeks preceding the study.

In fact, up-regulation of MFN-2 is necessary and sufficient for the induction of apoptosis in vascular smooth muscle cell [83]; in addition, it was recently observed that the MFN-2 interacting protein Trichoplein/mitostatin is downregulated in several human tumours [84] and deeply regulates mitochondrial morphology and tethering with ER, with consequent control in apoptosis levels [85].

Proponents of free trade consider that the unconditional MFN clause is the only practical way by which to obtain the progressive reduction of customs duties.

Therefore, it is tempting to speculate that the "increased" mfn levels in pink1 or parkin knockdown flies may reflect an increase in mitochondrial biogenesis in these mutants [17].

However, there are antibodies available against mammalian Mfn that have been reported to work for immunoprecipitation.