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This is very, very silly humour that largely exists outside the direction comedy has taken over the past 30 years, but it's capable of hitting the mark, nonetheless.
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As Toxey, the author of "Materan Contradictions," has written: In the space of twenty-five years, the government transformed the populace from a dialect-speaking, land-working, troglodyte peasant culture that largely existed outside the Italian nation into wage-earning, tax-paying, Italian-speaking state employees and blue-collar consumers . . .
The modifications act to attract or repel effector proteins that largely exist in multiprotein complexes and ultimately function to change the accessibility of the DNA to other complexes such as DNA and RNA polymerases and DNA repair machinery.
So he proposed the giant central structure that still largely exists today.
Beautiful pieces, to be sure, but relevant to a culture that now largely exists only in the past.
Previous reports have indicated that asymmetry largely exists in the lower third of the face [14, 23 25].
If you google girls who strip on FaceTime, you won't get a lot of joy; it's a trade that still largely exists within chat rooms and private inboxes.
However, LAM is antigenic, eliciting a strong humoral antibody response [ 22] and so it is likely that LAM largely exists within the circulation in the form of circulating immune complexes which would not readily cross the glomerular basement membrane.
OK, that perception still largely exists in some circles, but dude was really just a famous mid-level player in Canada's third-ranking political party in early 2012.
The I.P.O. may not have surprised industry analysts, but it certainly raised the profile of a Web site that had largely existed below the radar.
Indeed, the purchaser/provider split brought conflict for the first time to the NHS workplace, leading to divisions between primary and secondary healthcare provision that still largely exist today.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com