Comparison of our genes that are SL or SS with mps3 SUN domain mutants to genes identified in genome-wide SGA screen for interactors of the SPB components Spc110 and Cnm67 or the SPB regulators Stu2 and Mps1 also showed only limited overlap [ Figure 4A and data not shown (Costanzo et al. 2010; Greenland et al. 2010)].
(That's "SL" as in "Sport" and "Light").
Altogether, our data showed that HGS is SL partner of oncogenic β-catenin and its depletion induces apotosis in hepatoblastoma cell lines.
Recently, it was shown in HCT116 cells that RAD54B is SL with LIG4 (Oh et al. 2013), which encodes DNA ligase IV, a key protein involved in nonhomologous end joining, and suggests that the homologous recombination repair and nonhomologous end joining pathways can functionally compensate for each other.
The SL RNA generally contains two functional domains: an exon (i.e. SL) that is transferred to an mRNA and an intron that contains a binding site for ribonucleoprotein particle assembly (Sm) to facilitate splicing.
This suggests that MTBDR sl is sensitive for detecting FQ resistance caused by mutations in gyrA (the only gene that is targeted by MTBDR sl for detection of FQ resistance).
Dengue virus has a single-stranded RNA genome with positive polarity, a 5' m7GpppG cap, and a conserved 3'-terminal stem loop (SL) that is linked to proposed functions in viral RNA transcription and translation.
In this paper, we present Syn-Lethality, the first integrative knowledge base of SL that is dedicated to human cancer.
Employing this procedure for subcellular fractionation of a crude organelle preparation, we obtained a fraction of intact vesicles that is significantly enriched in SL marker proteins.
In relation to extrinsic aging, chronic exposure to UV radiation has been suggested to mainly cause skin damage known as photodamage, which is characterized by wrinkling, sagging and hyperpigmentation that is usually diagnosed as SLs (Hölzle, 1992).
