We propose this involves interactions with both the aromatic and the hydroxyl groups at both locations, as retaining one of these, that is replacement with Ser or Phe, caused only small or no changes in EC50.
Field was working with restricted ZFU, Zermelo-Fraenkel set theory with the axiom of choice modified to allow for Urelemente, objects that are not sets, but not allowing for any non-set-theoretic vocabulary to appear in the comprehension axioms, that is, replacement or separation (Field 1980, p. 17).
ZEBET is dedicated to all three facets of the 3Rs, that is, replacement, reduction, and refinement of testing in animals, which have been incorporated into the EU Directive 86/609 (Fig. 1).
Such observational studies will crucially underpin the design of an explanatory interventional trial by informing the hypothesis for justifying an IVIg intervention, that is, replacement of low Ig concentration to physiological levels versus immunomodulation.
In the occipital cortex and midbrain, there were smaller cells (reduced total protein/DNA ratio) and a corresponding increase in cell packing density (DNA concentration), features that are likely to reflect neuronal damage and "reactive gliosis," that is, replacement with smaller, glial cells (O'Callaghan 1988 , 1993 Roy et al. 1998, 2002; Roy and Sabherwal 1994, 1998).
At the same time, this symposium was meant to celebrate the 50th anniversary of the publication of the book "The Principles of Humane Experimental Technique" by Russell and Burch in 1959 in which the 3Rs principle (that is, Replacement, Reduction, and Refinement) has been coined and introduced to foster the development of alternative methods to animal testing.
The church's floor consists of pine board that are replacements installed during the church's 1968 restoration.
Also in the Dragon's cargo are several tiny satellites called CubeSats, each smaller than a football, that are replacements for items lost in the Orbital launch explosion in October.
But you can buy a vegetarian version from wholefood shops that is a reasonable replacement.
Maternal - a bull that is used for producing replacements.
VibraTip™ is a new technology that is intended to be a replacement source of vibratory stimulus.
