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Evidence suggests that inflammatory bowel disease-associated cancers arise from a larger field of colorectal mucosa that is "preconditioned" with a mutational burden that confers an increased propensity for further neoplastic progression, a phenomenon known as "field cancerization" (20, 21, 22).
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SPE analysis was performed on Oasis cartridges (Waters Oasis® HLB, 30 μm, 60 mg) that were preconditioned with 1 ml ethanol followed by 5 ml water.
However, it certainly played a crucial role when it occurred with the right timing and location in association with an environment that was preconditioned by the superposition of multiple (dynamical and convective) large-scale factors with different origins.
The results may provide a mechanistic explanation for the improved outcome to polymicrobial sepsis of rats that are preconditioned with heat shock, as well as a novel highlight for therapeutic intervention of severe infection.
Mice that were preconditioned with A1R agonists 24 hours before E. coli inoculation exhibited decreased TNFα and IL-6 sera levels and reduced leukocytes recruitment.
Rats that were preconditioned with sevoflurane were subjected to middle cerebral artery occlusion (MCAO), and the expression of TREK-1 protein and mRNA was analysed.
The extracts were combined and eluted with 100 mL dichloromethane through a 20-g silica column [Varian Inc. (Agilent Technologies), Santa Clara, CA, USA] that was preconditioned with ethyl acetate, dichloromethane, and hexane.
These 75%, aqueous solutions were loaded onto 500 mg C18 Bond Elut solid phase extraction columns (Agilent, Lake Forest, CA, USA) that were preconditioned with 5 ml HPLC grade methanol followed by 2.5 ml HPLC water.
The trend toward higher concentrations of PCr at 3,100 m suggests that placentas were preconditioned to store energy for use during ischemic/hypoxic stress.
The same section summarises the Presbyterian Church of Victoria's church and nation committee's view that history students "are preconditioned towards a negative view of western society".
"The positions are far apart, one requiring immediate departure, one saying that discussions will not take place if that is the precondition," Mr. Judeh said.
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