Sentence examples for that is apc from inspiring English sources

To investigate the effect of β-cateninE654 on Apc-driven tumour formation, we bred our β-catenin model with two mutant Apc knock-in mouse models, that is Apc +/1572T and Apc +/1638N.

In the same specimens, three further genes, that is APC, RARB2, and RASSF1A, proved to be hypermethylated at similarly high frequencies, and also discriminated well between tumour and normal tissue.

Other tumour suppressor genes were mutated in only a minority of sporadic breast cancers (<10%); that is, APC, ATM, BRCA1, BRCA2, MAP2K4, PTEN, p16, SMAD4, VHL, and the mismatch repair genes MLH1, MSH2, and MSH6.

Results are shown for polypoid adenomas, nonpolypoid adenomas and all adenomas together, divided into samples that were APC mutated or APC wild type.

Results are shown for polypoid adenomas, nonpolypoid adenomas and all adenomas together, divided into samples that were APC methylated or APC unmethylated.

Taken together, these data suggest that mTORC1 is a crucial, β-catenin-independent effector that is activated by Apc mutation.

Substantial duration of contact is thought to be required for the cell-cell interaction to be effective, e.g. for the TC to deliver the cytotoxins that kill the APC that is infected by viruses.

Because APC has similar affinity as PC for EPCR, an early event in the anticoagulant pathway is to generate APC that is associated with the endothelial cell surface.

The AAPC is a weighted average of the APCs that is calculated by joinpoint regression.

Thus, WTA qualifies as a bacterial ZPS that is processed and presented by APCs via the MHCII pathway [19].

For example in Xenopus, Axin was found to be at low concentrations relative to other pathway proteins, whereas in the mammalian cell lines, it was APC that was at low concentrations.