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We describe the results of computational investigations of a novel circuit that is able to trigger specific differential responses depending on the input standard used.
Interleukin-8 (IL-8) is a chemotactic cytokine that is able to trigger inflammation by recruiting and activating neutrophil granulocytes (Larsen et al. 1989).
S. cerevisiae grows far better at acidic than neutral or alkaline pH and consequently even a modest alkalinization of the medium represents a stress situation that is able to trigger a compensatory multifactorial response (for a review see [ 16]).
An example from Figure 2A is the activation of ErbB11: both the receptor monomer ErbB1 and the ligand EGF are needed to get the phosphorylated receptor dimer that is able to trigger downstream signaling events.
Our finding that TGF β can induce mesenchymal transition provides another secretory factor that is able to trigger mesenchymal differentiation in GBM, thus contributing to tumor heterogeneity and enhanced tumor aggressiveness.
DOI: http://dx.doi.org/10.7554/eLife.03058.004 Depletion of protein-coding transcripts is often achieved using RNAi-based techniques, which supply double-stranded RNA that is able to trigger post-transcriptional destabilisation of the mature mRNA and inhibit translation, predominantly in the cytoplasm.
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The predicted sizes and volume fraction of inclusions that are able to trigger the channel segregation effectively are consistent with the data obtained via microtomography characterization.
This paper assesses the sources of pressure at the landscape level that are able to trigger a transition towards a sustainable innovative waste-management system.
As biomaterials can have profound impacts on the host immune response the concept emerged to design biomaterials that are able to trigger desired immunological outcomes and thus support the healing process.
An elementary signaling mode is a minimal set of components that are able to trigger a certain signaling response autonomously.
In this study, we have demonstrated that erastin is a potent and specific inhibitor of system xc−-mediated cystine uptake and further elucidated the mechanism of action of this and other system xc− inhibitors that are able to trigger ferroptosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com