Desailly was born in Accra in Ghana, where, as fate would have it, his mother made a decision that irreversibly changed the course of his life; she married a French diplomat.
In normal liver function, ALDH1 functions as a cytosolic retinal dehydrogenase that irreversibly converts retinol (vitamin A) into retinoic acid [37].
Activated charcoal is an effective, inert, and nontoxic adsorbant that irreversibly binds intraluminal toxins and interferes with their absorption, especially for high molecular weight compounds [17, 18].
Results demonstrate that biomaterial-based gradients of S1P are short-lived in the tissue due to degradation by S1P lyase, an enzyme that irreversibly degrades intracellular S1P.
Because O6meG repair by MGMT is a stoichiometric reaction that irreversibly inactivates MGMT, which is subsequently degraded, the repair capacity of O6meG lesions is dependent on existing active MGMT molecules.
Fluorescent proteins that irreversibly change their spectral properties in response to light irradiation of a specific wavelength, or photoactivate, have become increasingly popular to image intracellular dynamics and superresolution protein localization.
Recent studies have shown that a number of deactivation pathways can occur in anthraquinones, including emission from tautomeric states following excited state internal electron transfer and from population of a dark, non-radiative state that irreversibly leads to a colorless molecule [34, 35].
The story of Zaion is set in 2004, four years after the American CDC discovers a meteorite-introduced virus that irreversibly alters the molecular structure of the human body and turns its victims into violent creatures.
It is composed of cross-linked protein residues that irreversibly form due to oxidative processes [18].
S1PL is an aldehyde-lyase that irreversibly cleaves sphingosine 1-phosphate (S1P) in the terminal step of sphingolipid catabolism.
Bearing no Cys residues, DelCys should not be able to be alkylated with AMS, a maleimide derivative that irreversibly adds 0.5 kD of molecular mass for each thiol modified [37].
