It is therefore necessary, in any cost-effectiveness analysis, to infer adverse event rates from error rates – a step that introduces further uncertainty.
Participants were also not provided with a definition of the term "sex," an omission that introduces further ambiguity into our findings by requiring participants to supply their own, inconsistent, meanings for the term.
In Ref. [ 5], Wodarz et al. noted that the few previous reaction-diffusion models of oncolytic virus spread [ 18, 19] include, in addition to basic spatial dynamics, one or more additional assumptions that introduce further complexity.
It therefore seems likely that epistasis will also structure evolutionary trajectories under more complex, realistic conditions that introduce further nonlinearities into the relationship between physical properties and selectable biological outcomes.
The practical situation is most often even worse than that, since the measurements are typically incomplete, noisy and sometimes dynamically not rich enough, that may introduce further obstacles to the structure/parameter estimation process [ 66, 89].
However, it is known that, within minutes of collection, peripheral blood gene expression profiles change significantly due to transcript induction and transcript degradation[ 1], and it is almost certain that the purification process introduces further changes in expressed transcripts.
The committee itself has previously joined the chorus of complaint but now advocates a system that would introduce further "multiple lines of financial accountability" and necessitate the establishment of (yet more) "robust procedures" to ensure this would operate as intended.
Moreover, AP MS interaction data are non-binary by nature for any multi-component complex; their conversion to binary pair-interactions is non trivial and relies on processing protocols that may introduce further biases in the final screening output [17], [19].
Limitations of our study pertain to its cross-sectional character, which precludes direct inference on causality, problems of reporting bias given the old age of the participants and the large time spans covered, and only limited control over confounding variables that may have introduced further bias, like sampling.
That's why the Prime Minister announced at the Conservative party conference that we will introduce further powers to regulate settings which teach children intensively and to intervene and impose sanctions where there are safety or welfare concerns.
Many now argue that instead of introducing further reforms, the government should raise wages and start spending again on infrastructure and education, and on developing the local economy.
