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We propose an conceptual framework that integrates input intensity, output intensity and associated system-level impacts.
These changes may be accompanied by changes in cerebellar gene expression (Laffaire et al., 2009; Moldrich et al., 2007) and in the number and morphology of Purkinje cells (PCs), the class of cerebellar neuron that integrates input from GCs, as well as other cells, and produces the sole output from the cerebellar cortex (Baxter et al., 2000; Necchi et al., 2008).
Abdomen contact induced transient activity in the transmidline interneurons of the P1 neuron cluster, a designated 'command center' for courtship behavior that integrates input from multiple sensory modalities (Kimura et al., 2008; Kohatsu et al., 2011; von Philipsborn et al., 2011).
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This paper describes the development of a method that integrates input-output (IO) table flows with SD modelling to improve the completeness of UM assessments.
mTOR is a major cellular signaling hub that integrates inputs from the upstream signaling pathways, including tyrosine kinase receptors, while also governing energy homeostasis and cellular responses to stress such as nutrient deprivation and hypoxia [ 24, 25].
Terrestrial vertebrates such as songbirds, bats, and primates rely on vocal networks that integrate input from breathing circuits [ 40- 44] to drive multiple vocal and respiratory muscles.
With the introduction of DAAs to 'real-life' settings, high accessibility and patient-centered symptom and adherence assessment will demand multidisciplinary team approaches that integrate input from both the patients and their close support persons [ 53, 55, 56].
CRMs act as modular units that integrate inputs from multiple TFs giving rise to a specific spatio-temporal output of gene expression [ 3].
mTOR is a serine/threonine protein kinase that integrates the input from multiple upstream pathways, and whose activity is stimulated by insulin, growth factors, serum, phosphatidic acid, amino acids and oxidative stress [27], [28].
Ideally, these models can drive a "learning engine" that integrates heterogeneous input data from an encounter with an infected patient and predict outcomes for possible interventions.
Although tap activates both anterior and posterior mechanosensory neurons, which mediate reversal and acceleration respectively, the neural circuit that integrates tap input in adult animals is biased toward reversal (Wicks and Rankin 1995).
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