Sentence examples for that determine efficacy from inspiring English sources

While the efficacy of AF cryoablation is well known, the thermal thresholds and mechanisms of cryoinjury that determine efficacy are not known thereby hindering development of the next generation of AF cryoablation systems.

Efficacy varied between different endpoints, such as parasitaemia or clinical malaria; however the underlying mechanisms that determine efficacy and its duration remain unknown.

The aim of our study was to investigate in detail the mechanisms that determine efficacy of agonists at individual classes of G-proteins coupled to M2 muscarinic acetylcholine receptors in natural membrane environments.

The resting habit of the vector is one of the most important factors that determines efficacy of IRS.

It is critical to dissect the key signaling proteins that determine the efficacy of tumor antigen-induced CD8+ CTL cytotoxicity to enhance anti-tumor efficacy.

However, crucial factors that determine the efficacy of miRNA-mediated target gene silencing are poorly understood.

The insights gained into the chemical and physical mechanisms that determine the efficacy of the technology will be outlined.

Little is known about the enantioselectivity of the processes that determine the efficacy and environmental fate of natural compounds with potential to be used as environmentally-friendly agrochemicals.

The factors that determine the efficacy of PDT (drug and light doses, drug to light interval, oxygen concentration and tumour margin) are also emphasized.

The development of our understanding of the pharmacokinetic (PK) and pharmacodynamic (PD) principles that determine antimicrobial efficacy has advanced substantially over the last 10 years.

As the number of TS inhibitors available for general clinical use increases, further research is needed to elucidate the critical molecular and biochemical elements that determine the efficacy and tumor specificity of each compound.