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smyRNA (structural sequence motifs yielding to ncRNAs) is a simple ab initio ncRNA discovery tool which is based on the premise that certain sequence motifs act as important determinants of ncRNA structures and have differential distribution among ncRNAs and the background genome sequences.
GC rich regions and sites close to the ends of sequence reads typically show elevated errors rates [ 19] and it has also been shown that certain sequence patterns, especially inverted repeats and "GGC" motifs are associated with an elevated rate of Illumina sequencing errors [ 10].
Moreover, Bagchi et al. (2002) revealed that certain sequence changes in HSF4 resulted in abnormal expression of HSPs and thereby influenced the function or level of HSPs.
We demonstrate that certain sequence motifs are preferred over others as primers where the six nucleotide sequences at the 3' end of the primer, as well as the sequences four base pairs downstream of the priming site, may influence priming efficiencies.
We hypothesize that certain sequence combinations in the flanking regions of SNPs predispose toward mutation due to effects on primer strand geometry within the polymerase active site and interactions with side-chains essential for proper catalytic function, possibly altering solvation dynamics within the active site.
If the above concerns were not enough, two reports in the literature showed that certain sequence motifs in siRNAs can trigger type I interferon production via activation of toll-like receptors (TLRs) 7 and 8, thereby compromising the sequence specific knockdown effects of the RNAi pathway (Hornung et al, 2005; Judge et al, 2005; Robbins et al, 2008).
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During this time, he produced a proof that asserts that certain sequences of integers defined through the power function contain an infinite number of prime numbers.
If it is found that certain sequences of letters planet, tree, woman are used with identical meanings in a number of different books, one can be sure that the languages used in those books are of common origin.
The technique was developed in 1984 by British geneticist Alec Jeffreys, after he noticed that certain sequences of highly variable DNA (known as minisatellites), which do not contribute to the functions of genes, are repeated within genes.
Variety declared it was "not Chaplin's best picture" but that certain sequences were "hilarious".
Whatever we may think of the bleed-through among media platforms, it's not surprising that certain sequences in "The Walking Dead" resemble challenging levels on "Call of Duty" and that "Game of Thrones" makes the body count of "The Hobbit" look quaint.
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