Studies focused on individual histone modifications have shown that certain marks, such as H3K4me3, associate with active promoter regions, whereas others, such as H3K27me3, are pronounced at silent promoters [ 75].
To say that certain features are marked out as morally salient is not to imply that the features thus singled out answer to the terms of some general principle or other: we will come to the question of particularism, below.
Wang et al. combined the histone acetylation and methylation ChIP-Seq data to observe that certain histone modification marks tend to be grouped for activating gene expression [ 18].
Due to the uniform distribution of the marks among the n + 1 points in C i, and the marks are irrelevant to the points, the probability that x i has a certain mark (among the n + 1 marks) equals to 1/(n + 1).
A national curriculum was introduced and new exam boards were formed that allowed all the pupils who attained a certain mark to receive a certain grade.
It hit a certain mark so definitively that you had to tell your friends about it and thrust it into their hands.
Parmenides argues that human thought can reach genuine knowledge or understanding, and that there can be certain marks or signs that act as guarantees that the goal of knowledge has been reached.
They should only draw it to a certain mark.
In such a period of rapid wealth creation it's hardly surprising that certain other marks were raised.
It is a neat depiction of one of Escher's enduring fascinations: the contrast between the two-dimensional flatness of a sheet of paper and the illusion of three-dimensional volume that can be created with certain marks.
