Sentence examples for that cannot be internalized from inspiring English sources
In this regard, the previously noted potency of curdlan as an innate stimulus appears to relate to its ability to form large particles that cannot be internalized.
We recently found that challenging HCECs with either purified flagellin or invasive strains of P. aeruginosa resulted in an up-regulation IL-1β at both mRNA and protein levels but not in the secretion of IL-1β (Yu et al unpublished results), suggesting that either flagellin cannot be internalized or Ipaf-caspase axis is not functional in HCECs.
We demonstrated that large, but aggregated or amyloid fibrils of hPrP90-231 cannot be internalized and cause cell death.
It is important to note that the Lys24AlaMet27Ala, non-CALM binding mutant of VAMP8 cannot be internalized but, as we show in this work, is able to form SNARE complexes with its cognate plasma membrane SNARE partners.
Importantly, the Lyp1-K10XR proteis is efficiently delivered to the PM but cannot be internalized or degraded by the heat-induced endocytic response.
Thus, GPI anchoring of GH or ecGHR increases the probability that the GPI-anchored proteins will co-segregate with the native GHR on the cell membrane and constrain the GHR in a conformation that cannot be readily internalized.
It seems possible, based on our findings, that fibrils are internalized by microglia (or other cell types) and are then degraded or digested into smaller fragments that cannot be detected by our antibody.
Together with the lack of gp78/AMFR correlation with HER2 [41], this suggests that gp78/AMFR labeling defines a substantial cohort of tumors that cannot be treated with HER2-targeted therapy and that should, in the absence of Cav1, internalize AMF/PGI.
The non-absorptive text is one that cannot be satisfactorily internalized morally, intellectually, or emotionally by a reader.
Results obtained using such models suggest that environmental externalities should be internalized by environmental policies.
That cannot be overemphasized.
