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These results could not be obtained using chemical proteasome inhibitors that cannot be directed to specific tissues.
Advantages of cluster RCTs over individually randomised controlled trials include the ability to study interventions that cannot be directed toward selected individuals and the ability to control for "contamination" across individuals, that is, the unintentional spillover of intervention effects from one treatment group to another.
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If the weapons used are so inaccurate that they cannot be directed at military targets without imposing a substantial risk of civilian harm, then they should not be deployed.
The ruling states that the ban cannot be directed at headscarves explicitly but must be part of an internal rule requiring all employees to "dress neutrally".
The sunlight that falls on the exteriors of buildings cannot be directed or changed in quality, but it can be reflected or absorbed in a wide range of modulation by the relief and texture of surfaces.
A wiretap cannot be directed at a U.S. facility, the official said, without finding probable cause that the phone lines or Internet addresses were being used by agents of a foreign power — or by someone spying for or acting on behalf of a foreign government.
However, it must be born in mind that such challenges are likely to evoke both pharyngeal and laryngeal reflexes as the ammonia vapour cannot be directed at a single receptive field.
Colleges and high schools cannot be directed to handle concussions the way the N.F.L. now does.
"Though less lethal, these attacks, using unguided rockets which cannot be directed at specific targets, violated international humanitarian law and cannot be justified under any circumstance".
"They cannot be directed at a specific military target, and their effects cannot be limited as required by international law," a spokesperson told us.
HIFU cannot be directed through air-filled viscera such as the lung or bowel and other obstructions such as bone can absorb or reflect an ultrasound beam.
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