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Only those drugs that bound to serotonin receptors blocked infection.
Monsanto had sought a patent for five ESTs that bound to DNA in corn leaves.
The researchers attached the tetrapeptide to FKBP52 with a second protein that bound to both molecules.
The resulting compounds were potent dimerization inhibitors that bound to the enzyme in a similar conformation as the fragments.
We further identified fragment hits that bound to subpockets of sEH called the short and long branches.
We selected a single-domain antibody (VH9) that bound to the human domain with a dissociation constant of 44 nM.
The high oligomer concentration at the furfurylic alcohol surface caused the formation of oligomer clusters that bound to each other to generate the porous and electrically conductive pellicle.
Moreover, Ubvs that bound to two distinct sites on the intracellular adapter Grb2 could be combined to generate a potent inhibitor that functioned in cells.
The aptamers that bound to L. monocytogenes were isolated using centrifugation, PCR amplified, and purified to yield an enriched ssDNA pool suitable for further rounds of selection.
Among the three drugs that bound to the DNA-Topo I complex, SN-38 had the strongest relative binding affinity, and CPT had the weakest relative binding affinity.
Detailed characterization of an Ubv that bound to the cell-surface receptor human epidermal growth factor receptor 3 revealed tight binding in the single-digit nanomolar range.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com