This palaeoscenario may have favoured species more adapted to drier and highly seasonal climate, consequently leading to a retraction in the geographical range of many arboreal savanna taxa that became restricted to areas with moist climatic conditions [ 17, 18].
This indicates that once restriction is present in one area of life, this becomes a risk factor or risk marker for further areas of life to become restricted.
In summary, the genome of T. turnerae suggests that of a facultative endosymbiont that either maintains a significant ecological niche outside of its host, or of a bacterium that has only recently become restricted to the intracellular environment.
It is for instance known that some RNAs become restricted to the posterior pole by selective degradation protection mechanism (reviewed in Lipshitz and Smibert, 2000).
People who suffer from body dysmorphic disorder think that a feature of their body, such as their nose, is so undesirable that their lives become restricted.
More recent studies have shown that ECM formation can become restricted to tissue surfaces and interfaces by a mechanism utilizing surface de-repression of integrin-dependent inhibition of matrix assembly and that this enables self-organization and maintenance of tissue boundaries [26].
Interestingly, the EdU label were preferentially at the bottom of the newly formed epithelial folds at the end of metamorphosis, suggesting that the proliferating adult cells become restricted to the bottom of the fold, which resembles the crypt in adult mammalian intestine where stem cells reside [ 23– 25].
Because motions of molecules become restricted, radial pressure increases more than that in the axial direction.
This is supported by the example of Sfmbt2, which shows imprinted expression in the blastocyst and throughout the early postimplantation embryo that later becomes restricted to extra-embryonic lineages [ 36].
Instead, just as radio survived the advent of TV, culture will remain a part of the discipline, but widespread adoption of sequence-based approaches might mean that it becomes restricted to a limited number of settings.
