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James said he admired Derek Jeter — "that backbone" of his beloved Yankees.
Structural, dynamic, thermodynamic, kinetic and biochemical studies reveal that backbone circularization does not prevent the adoption of the natural folded structure in any of the circular proteins.
Here, it is recognized that backbone cyclization also reduces the chain entropy of a flexible peptide linker in the folded state.
We hypothesized that backbone compliance may play a role in protein protein recognition and in the mechanism of binding of small-molecule compounds to protein surfaces.
There are good ways of coupling these circuits to the fiber optic cables that backbone the internet and so they're being used by companies like IBM and Luxtera to send and receive more and more data.
Finding a mentor who provides "that backbone you need" has made all the difference, said Cameron Anderson, 21, of Tampa, Fla., who entered foster care at 15 after he got into trouble with the law, then lived in group homes.
Similar(9)
Our experimental results show that backbone-guided local search is effective on overconstrained random Max-SAT instances.
The results show that backbone-correlated motions are a fundamental property of β-sheets and that they can be of functional relevance.
Computational chemistry has shown that backbone-alkylated imidazoles ought to be efficient ligands for transition metal catalysts with improved carbene-to-metal donation.
The results clearly indicate that backbone-modified PNAs are good candidates for the development of very efficient drugs based on anti-miR activity, due to their enhanced bioavailabilities, and that overall anti-miR performance is a combination of cellular uptake and RNA binding.
We found that backbones were modelled well, with an average RMSD100 score of <0.80 Å measured over all backbone atoms, similar to previously reported values for backbone models (Grigoryan and Degrado, 2011).
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