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Indeed they have begun to reveal pathways and cellular processes that are subverted in cancer and that may be promising drug targets.
Thus, the important and essential issues plaguing CML therapy are determination of the gene changes that cause disease progression, determination of the normal pathways that are subverted on the road to blast crisis and whether we can restore these pathways to put patients back into chronic phase.
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This plan, according to United States officials, is nothing more than a fight against drugs that are subverting Colombia's democracy and poisoning youths across the United States.
They join an increasingly varied and lengthy list of TV shows that are subverting the idea that for women, all narrative roads lead toward and end with coupledom.
The images were redolent of an age of permissiveness that was subverted, arguably perverted, by a male-dominated culture.
In Tribeca, he deploys the cornices and rows of uniform, period-style windows as a sign of normalcy that is subverted by the fragmented facades.
It is a control and technical virtuosity that is subverted in this particular move, however, to a graceful image of poised flight that recalls the sylphides perched on rocks in 19th-century ballet lithographs.
Secretary General Kofi Annan underwent an hour and 35 minutes of questioning from Paul A. Volcker yesterday, the third time he has been interviewed in his office by Mr. Volcker or a member of the three-man panel he heads, which is investigating the United Nations-run oil-for-food program in Iraq that was subverted by Saddam Hussein for an estimated $1.7 billion.
University of Michigan scholar Diane Sampson, publishing in a collection entitled "Bad" Mothers: The politics of blame in twentieth-century America, saw Baird as trying to establish motherhood as a 'site' in elaborating her qualifications for Attorney General during her confirmation hearings, an effort that was subverted by her affluence and her earning far more than her husband did.
Inflammation is an important physiological host defense mechanism that is subverted in multiple chronic diseases.
These findings provide a new regulatory pathway that is subverted in cancer cells, a novel means of attacking TIC and non-TIC aspects of BLBCs and a lead molecule that confers sensitivity to low µM TMX.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com