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Recently, studies into Lactobacillus rhamnosus have shown that this bacterium contains pili that are indispensible for interactions with human mucus [31].
This interpretation is strengthened by life cell imaging experiments showing the importance of mitochondria in dendritic spines for the plasticity of synapses [50] and secondly by developmental gene expression studies of the whole cerebellum where parallel up-regulation was found for genes that are indispensible for synaptic activity and plasticity [51].
The benzoquinone embelin acts as a weak mitochondrial uncoupler, and this prevents energy-intensive processes such as proliferation, migration, and capillary tube formation that are indispensible for neoangiogenesis during tumor growth and wound healing.
Phospholipids in cell membranes, actin and myosin in muscle cells, or collagen and hydroxyapatite in bones are chemical structures that are indispensible in the biology of a vertebrate and exist in all vertebrates.
Polyamines are multifunctional polycations that are indispensible for cancer cell survival, influencing a range of biological processes including DNA synthesis and stability, replication, transcription and translation, ribosome biogenesis, and protein phosphorylation [152].
The public health community can contribute to the establishment of and participate in routine training programs and exercises that are indispensible components of preparedness and response to chemical incidents.
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"From founding this company to guiding its growth into a trusted global brand that is indispensible to millions of people, I have always sought to do what is best for our franchise," said Jerry Yang.
ZNF143 was previously reported as one of the several transcription factors responsible for maintaining the normal transcription levels of the mammalian mitochondrial transcription factor A (TFAM), a nuclear-encoded mitochondrial transcription factor that is indispensible for the expression of key mitochondrial-encoded genes and for the replication of mitochondrial DNA.
This is rather unexpected, as it implies that either these components are associated only with those Rabs that are 'indispensible', or that the Rabs only add functionality to existing processes, or, as seems likely in at least some cases, new Rabs can add transport steps without the cell having to evolve new coats, tethering complexes, or SNAREs.
In spite of all the things that are believed to be indispensible for the Best Foreign Film award — advertisements, lobbying, promotions and an unlimited reserve of cash — most of the nominations in the recent past, let alone the eventual prize, have gone to exceptional films.
We have previously shown that ROS are indispensible for PKG stimulation of the neuronal-type KATP channel [25].
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