Sentence examples for than activating from inspiring English sources

Biomarkers downstream of PI3K/AKT/mTOR signaling may reflect pathway activation more accurately than activating mutations, since the effects of active signaling will be amplified across the entire tumor cell population through paracrine growth factor receptor pathways.

Importantly, the MAPKKK MEKK3 had the opposite effect to LRRK protein overexpression on Wnt signaling, repressing rather than activating DVL1-mediated TOPflash activation (Fig.  2D).

Nonetheless, recent finding from Crabb and colleagues suggested that ethanol is capable of inhibiting (rather than activating) hydrogen peroxide-induced AMPK activation in hepatoma cells [23], suggesting a likely paradoxical role of AMPK in ethanol-elicited effects.

TFIIS is primarily an elongation factor and TFIIS knockdown should primarily affect the efficiency of actively transcribed genes rather than activating new pathways.

Moreover, the data indicate that it might be important for drug discovery strategies to maintain Cdk5 activity at wild-type levels, rather than activating or inactivating it excessively.

However, recent experiments suggest that the role of Mrc1 at stalled replication forks is more than activating Rad53, since mrc1 AQ cells, defective in Rad53 activation, are not defective in replication fork initiation or progression [18,20,21].

However, in contrast to cell culture data, the rGH-PAL activity was substantially repressed rather than activated in 100 nM T3 concentrations (Fig. 10D-D').

It was found that at pH 6, the PAN-g-PVAm membrane showed almost two times higher adsorption capacity than activated carbons, and about 20 times higher than some synthetic activated carbons.

Activated GoA heterotrimers can seemingly dissociate more readily than activated Gs heterotrimers, and this may account for Gα-specific activation of Gβγ-sensitive effectors [ 47].

Non-activated syringe irrigation showed less apical extrusion of irrigating solution than activated methods.

DPE-L activity is also context dependent, exerting a greater effect in constitutive than activated transcription.