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Given the different tests underlying the individual significance, differential expression was assessed by applying p-value < 0.05 (restraining FDR < 0.1) and fold-change ≥ 2.0.
This approach should reduce the number of false positive statistical results from the several hundred individual statistical tests underlying this pool of data and should be more discriminative than the analysis of individual studies, if the inter-study variabilities are small.
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The extremely high negative predictive values of both molecular tests underlie their importance in screening for high grade lesions and are in concordance with previous publications[ 18].
In order to test underlying pathway mechanisms of EtOH-induced effects, slices were treated with NOS and MAPK p38 inhibitors.
The autologous serum skin test may be used for non-specific autoantibodies against either IgE or the high-affinity IgE receptor, 8 and there are some specific provocations that may be used to test underlying causes.
On the other hand the UKCAT and UMAT focus largely on testing candidates' fluid intelligence in terms of mental processing, reasoning and decision making without testing underlying background knowledge.
The Fisher's exact test (the statistical test underlying the CatFisher tool) identified three transcription factors over-represented in leaf EST libraries (a CCAAT-HAP3 in the apical shoot library, and a CCAT-HAP5 and C2C2-YABBY in the shoot meristem library).
As performance in the standing balance test relies more on neurocognitive function than either of the other two tests, 38 underlying neurodevelopmental pathways could partially explain our findings.
Post-estimation tests for underlying assumptions included Hosmer-Lemershow goodness-of-fit and Schoenfeld residuals for logistic and proportional hazards models respectively.
Assuming that the test-statistics underlying the two-sample t-test were independent across genes and using the estimator of Schweder and Spjøtvoll [ 21], the number of genes with unchanged ratios was of the order 64%.
Testing criteria assist in determining inputs for testing the underlying system as well as combining them in such a way that they effectively exercise it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com