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Treatment was based on clinical features, not on results of the rapid tests under evaluation.
An overview of the performance of each of the tests under evaluation in our study is provided in Table 2.
Samples missing a result for any one of the tests under evaluation were excluded, so that we could directly compare sensitivity and specificity estimations across the different tests.
The study was reported according to STARD guidelines which includes method of recruitment of patients, orders of test execution, and numbers of patients undergoing the tests under evaluation and the numbers of patients with the reference standard [22], [23] (Figure 1).
The relative sensitivity and specificity of the tests under evaluation and Cohen's K value were calculated.
Diagnostic tests under evaluation included laboratory tests, imaging and physical examination.
Similar(49)
In the ROC analysis, the expert consensus was used as the gold standard but this approach is problematic because ROC analysis should have a gold standard independent of the test under evaluation.
A positive MODS was not considered as part of the 'confirmed TB' group definition because this was the test under evaluation.
Xpert was the index test under evaluation.
The index test under evaluation was MRI of the axial skeleton.
Item 5: If intrarater reliability were tested, were raters blinded to their own prior findings of the test under evaluation?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com