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"A separate set of documentation has been prepared for these purposes which removes reference to RIPSA but otherwise requires the same tests of necessity and proportionality to be met.
However, in assessing their relative contribution towards ERK-mediated biologic response investigators have relied on tests of necessity, not sufficiency.
However, in assessing the relative contribution of MEK1 and MEK2 towards ERK-mediated biologic response each of these studies has relied on tests of necessity, but not sufficiency.
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Although Mr. Romney professed to "love Big Bird," PBS did not pass his test of necessity.
The most robust possible study design would be to do both: insert a disease mutation into a wild-type cell line – thereby testing for sufficiency of the mutation for disease – and correct the disease mutation in a patient-specific iPSC line – thereby testing for necessity of the mutation for disease (Liu et al., 2012; Reinhardt et al., 2013).
Its recommendation is: "All capabilities which provide the content of an individual's communications should be subject to the same legal safeguards, ie they must be authorised by a secretary of state and the application to the minister must specifically address the Human Rights Act 'triple test' of legality, necessity and proportionality".
Lesion-deficit correlation studies are important because they can provide a critical test of the necessity of the visual processing carried out by the left pFG and also reveal novel insights about the basis of visual recognition deficits in pure alexia.
The home secretary and some law officers decided to use the case to test the defense of "necessity," in which a killing is committed to save one's own life other than in direct self-defense.
The next step tests the necessity of two-point search based on the observation that a two-point search should be performed if this distance for any PU is equal to one.
Specifically, there has been uncertainty about the frequency and utility of daily testing; the necessity of SMBG in all women with diabetes during pregnancy; the timing of self-monitoring measurements and whether preprandial or postprandial testing was superior; and the ideal thresholds for implementing changes in therapy [ 4].
Further information on specific effects currently not included in risk assessment (e.g. immunotoxicity, genotoxicity, multi-generation tests, necessity of further test organisms such as sediment organisms living and grazing on the sediment as well as aquatic macrophytes) (see "Alternative test systems").
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com