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Disease progression categorical analysis (PDCA) used the categorical tests for survival data (CTSD) approach described in Section 2 of Additional file 1: Materials and Methods.
Time to tumor take was compared using log-rank tests for survival and comparison between animal groups was analyzed by the Mann–Whitney U-test, all tests were two-sided.
Log-rank tests for survival differences were all significant, except for common mental disorders, BMI, race and marital status among men; and common mental disorders and smoking among women.
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Periodically, samples of the cells were removed and tested for survival.
One-way or two-way ANOVA with Tukey's test was used for comparative analysis, Log-rank (Mantel-Cox) test for survival analysis, *P < 0.05; **P < 0.01; ***P < 0.001, ****P < 0.0001.
Mann-Whitney test was used for morphometric data and Log Rank test for survival curves.
Additionally, all strains were tested for survival of oxidative stress, a trait associated with microbial pathogenicity.
The Mann-Whitney test was used for morphometric Giemsa-staining data and the Log Rank test for survival curves.
All isolates were tested for survival of oxidative stress exerted by tert-Butyl hydroperoxide, a stable organic analog of H2O2.
A second UAS-GABABR2-RNAi line (GBRi-V; from VDRC) was crossed to the Dilp2-Gal4 flies and tested for survival at starvation.
Both i.d. (Fig. 3A) and i.n. (Fig. 3B) vaccination with Schu S4 ΔpurMCD increased the overall survival of infected mice over the naïve controls based on a trend test for survival probabilities (P<0.0001) [21].
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