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The colonies were further isolated and identified according to their morphological, physiological and biochemical tests characteristics.
The overall assessment underlined problems in several key steps: reporting detailed information from primary studies about the study design and patient characteristics, reference and index tests characteristics, and review methods.
As already shown [19], this is only possible by combining test results with expert opinions on the tests' characteristics.
Bayesian models were developed for estimating both the malaria prevalence using different diagnostic tests (microscopy, PCR & ELISA), without the need of a gold standard, and the tests' characteristics.
Estimating the malaria prevalence in a specific setting is not straightforward, particularly when considering the lack of a gold standard [9], [34] and the variability of the diagnostic tests' characteristics.
Though some results are expected, e.g. PCR more sensitive than microscopy, a standardized and context-independent quantification of the diagnostic tests' characteristics (sensitivity and specificity) and the underlying malaria prevalence may be useful for comparing different sites.
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This may have affected test characteristics.
Detailed test characteristics are detailed in Table 3.
Table 7 FSM(P) and test characteristics FSM characteristics Test suite length Number of resets Avg.
All tested characteristics were influenced by the formulation modification.
In this context the known test characteristics function as background information, b.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com