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The major limitations of our approach concern a lack of representativeness if care was not taken to adequately survey the target communities in order to guide recruitment and snowball initiation points, and generalisability to a wider population if statistical inference and hypothesis testing was desired.
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If information on each compound from every test is desired, then non-tiered approaches are more useful.
Overall 19 tests were desired by at least 50% of respondents in at least one country, while only 8 tests were actually used by at least 50% of respondents in at least one country.
Thus, if a 4- or 12-h test is desired for finding CL, Tk-GV fitting appears to provide an accurate (i.e. relatively unbiased) method of predicting CL for 24-h, even in the presence of ascites.
There was a growing awareness of the importance of factors other than test design in determining whether tests would have the impact that was desired.
Otherwise, for non-confidently predictable patients, further measurements and testing may be desired.
The number of transformants was increased by one order of magnitude and about 90% of tested colonies were desired integrants using in vivo assembled deletion cassette containing longer flanking homology.
Thus, the most effective test suite is desired to be executed as soon as possible.
We have also used the approach to design multi-country trials where each country's cluster sizes and variance parameters differ, but a common test across countries is desired.
Fixed-effect models are desirable when data partitions are known to exhibit significant heterogeneity or when a statistical test of such heterogeneity is desired.
Fixed-effect models are desirable when data partitions are known to exhibit significant heterogeneity in parameters such as c, κ or π, or when a statistical test of such heterogeneity is desired.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com