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The most useful study designs are likely to be those that enable us to also gather perspectives from persons with little or no interest in the testing under investigation.
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Even when only simple summary measures are appropriate, the strong correlation between sensitivity and specificity and their dependence on differences in diagnostic threshold across studies, creates the need for tools to summarise properties of the diagnostic test under investigation.
Administrative data algorithms were considered the index test (ie, the test under investigation).
Patient inclusion was never dependent on the result of the non-invasive test under investigation.
Based on the test under investigation, included studies were tagged as imaging studies, laboratory studies or other.
Following sampling for microscopy and culture, part of the remaining inoculum was used for the rapid direct test under investigation.
A relevant study for the hypothesis tests under investigation in this paper is Fagerland and Sandvik [ 7].
The likelihood of the relationship between latent disease, the new test under investigation and the other tests is then maximized to yield sensitivity and specificity estimates [ 22].
A common feature of diagnostic research is that results for a diagnostic gold standard are available only for patients who are positive for the test under investigation.
However, with respect to specificity and the absolute values in the borderline and pathological range, we found major differences between the tests under investigation.
A common feature of diagnostic research is that results for a diagnostic gold standard are available primarily for patients who are positive for the test under investigation.
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