The decision on continuation of the study was based on the confirmatory test of the primary variable.
The interaction term is necessary in the model to allow the test of the primary hypothesis on the 4-month post-intervention measurement.
We aim to demonstrate non-inferiority of the laparoscopic sacrohysteropexy at both 1 and 5 year (i.e. two tests on the primary endpoint will be performed).
Secondly, we imputed missing values [ 46] for 28 wk and 36 wk cortisol concentrations and re-analyzed the data as a sensitivity test on the primary models.
The largest increase in positive patients was found when we used all tests on the primary sample, compared with direct PCR only.
Following published recommendations on statistical analysis for Phase II trials, [ 46, 47] we used a statistical significance criterion of p <0.10 for a two-sided test on the primary outcome variable.
Every patient who entered the study underwent baseline assessments, including medical history, physical examination, performance status, HER2 testing (either on the primary tumour or on a metastatic site), electrocardiogram and chest X-ray.
The PFS and OS rates were estimated and plotted using the Kaplan Meier method and compared using the stratified log rank test for the primary analysis on the intention‐to‐treat population.
"BrightLine is part of a much larger strategy in the advanced-TV space," said Lou Paskalis, vice president for global media, content development and mobile marketing at American Express, as the company tests initiatives on the "primary screen," as in the TV set, and the second screen, as in a smartphone or tablet.
The second set of tests focused on the primary objective of the project - that of achieving unconditional precision synchronisation and efficient video multiplexing.
