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The Simon Broome British Heart Foundation study (SBBHF) of 409 individuals was used for the replication of the FH clinical diagnosis methods comparison between the Simon Broome FH criteria and the DLCN score, and for the testing of the mutation detection association with TC and TG quartiles.
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Of twenty random dogs tested for the mutation, one carrier of mutant allele 1 was identified.
Testing of the neutral mutation hypothesis for the evolution of cultivated monocot hb genes was performed by estimating the Tajima's D value.
Testing of the neutral mutation hypothesis was performed by calculating the Tajima's D value using the DNAsp program (http://www.ub.edu/dnasp/).ub.edu/dnasp/
*Pearson's two proportion test Analysis of the mutation spectrum of MCR region of SMAD4 gene revealed 16 mutations in total.
Like cancer testing, earlier detection of the mutation can prevent the disease, improve survival rates and reduce medical costs.
Tests of the Vmat mutation for night sleep revealed a significant genotype × sex interaction, partially confirming the GWAS observation.
We also tested the effect of the mutation of the proximal CRX binding element in the 79+134 NXNL2/NXNL1 fusion construct.
In parallel, we tested the influence of the mutation on the regulation of a firefly luciferase reporter for the StAR promoter (StAR −1300bp-luciferase −1300bp-luciferase previously reported to be down-regulated by FOXL2 [32].
In Zhan and Clark [47, 48], a solution for the generation of test data using the mutation testing is described.
First we present concepts from the multi-objective optimization field and we review mutation testing of SPLs, the adopted mutation approach and tool.
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