Sentence examples for testing of the compounds from inspiring English sources

Spectroscopic studies and cell image testing of the compounds showed their potential to be used as probes for bio-imaging.

During subsequent biological testing of the compounds synthesised here, we noted a cumulative loss of activity for several of the active compounds, suggesting that they may show instability.

The xenotransplant model has also been successfully used for the preliminary pre-clinical drug testing of SCH66336 and SXG393 (Peters et al, 2001; O'Hare et al, 2008) and although this model is not without limitations it does enable the effective testing of the compounds on the T315I mutation in vivo.

For testing of the compounds, cells were harvested, counted, and plated into 96-well plates at 1 × 104 cells per well in MEM-Eagles supplemented with 10% fetal bovine serum, and incubated for 24 hours at 37°C in a 5% carbon dioxide atmosphere.

It is necessary to take several samples for bioanalysis during the experiment: I. aECF samples a. for thermostability testing of the compounds studied (sampled before and after incubation in aECF without the brain slices) b. for measurement of Cbuffer – the final concentrations of the unbound compounds in aECF (sampled at the end of the 5 h incubation with the brain slices) II.

The advantage of using intact growing JEG-3 cells is that they allow testing of the compounds under conditions that closely resemble the tissue/physiological situation in which the drug must first cross the plasma membrane before it can reach the target (STS) enzyme.

Tests of the compounds confirm suitability for ALK + MET + EGFR polypharmacology optimization (Table 1).

Tests of the compounds for functional activity utilized intracellular Ca2+ mobilization.

The testing concentration of the compounds was set based on the prior cytotoxicity of other cancer cell lines.

C Sixty hopes to begin tests of the compound in people soon.

The couple said they were negotiating privately with a pharmaceutical company to test some of the compounds they have discovered and possibly turn them into drugs.