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Additional file 1: Supporting information contains the PET images of 89Zr-radiolabelled cetuximab and trastuzumab; description of the purification of mAbs, immunoreactivity testing of modified mAbs, cell uptake assay, in vitro pretargeting assay, and radiosynthesis of [18F]TAF; and ex vivo biodistribution results for pretargeted experiments and 89Zr-radiolabelled cetuximandand trastuzumab.
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We designed the HCV DOT trial to test the efficacy of modified directly observed HCV therapy provided on-site at a methadone clinic.
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Brookfield Rotational Viscometer was employed to test the viscosity of modified emulsified asphalt with the passing of time.
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However, the inability to produce large quantities of transgenic seed has limited the functional testing of the modified oil.
In vivo testing of this modified construct in 18 NHPs showed conservation of hepatocyte transduction but complete elimination of hepatotoxicity, even with sustained shRNA expression for 50 days.
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