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Thus, C. elegans is potentially amenable to genetic testing of interactions between O-GlcNAc cycling and insulin signaling/phenotypes.
The proportional hazard assumption will be evaluated using log-log survival plots, examination of Schoenfeld residuals, and testing of interactions between variables and time.
A major strength of this study was the large sample size that enabled testing of interactions between males and females, and separate reporting of results for men and women.
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However, some caution should be used in the interpretation of this result given the lack of statistical significance in the testing of interaction between the cohort group and sex.
Tests of interactions between input parameters showed that 62% of parameter pairs tested had significant interactions underlining the complex nature of the model structure.
When men and women were analyzed separately, effects seemed roughly similar across genders (see Table 6), and post hoc tests of interactions between gender and trauma type in predicting loneliness were non-significant.
When men and women were analyzed separately, effects were clearer among women than among men (see Table 4), although post hoc tests of interactions between gender and trauma type in predicting social support were not significant.
Online supplementary appendix 5 includes the details of additional, prespecified analyses, including tests of interactions between interventions, subgroup analyses and tests for between-cluster spillover effects.
However, tests of interactions between data source, deprivation, and time period (or sex) did not provide strong evidence for statistical differences between these groups.
Formal tests of interactions between residence and each of the characteristics of interest did not yield any statistically significant results, therefore pooled results, adjusted for residence, are presented.
Tests of interactions between treatment effect and HOXB13 analysis were performed by including product terms in the models, as well as other prognostic factors (tumor size and HER2).
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