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For example, yeast two-hybrid studies testing interactions of PRC1 components demonstrated that a CBX8 Gal4 activation domain chimera interacted with Gal4 binding domain chimeras expressing either the carboxy-terminus of Af9 or Rnf2.
However, testing interactions between all pairs of SNPs would have greatly increased the multiple-testing problem.
Standard software for family based genetic association with quantitative traits (such as QTDT) do not readily allow for testing the significance of gene-gene interactions, but QTDT does allow for testing interactions between covariates.
The deviance test (p ≤ 0.001) was applied for testing interactions.
This was done to examine change over time by testing interactions between SHC and time.
When testing interactions, our approach is to follow the standard statistical methodology.
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ii) the mutual information-based statistics for testing interaction between two unlinked loci.
The type of meal × order of testing interaction (F 1,67) = 2.08, n.s) was also non-significant.
The significance level for testing interaction between factors was set at 10%.
Following Cohen & Cohen's approach [ 35], moderated regression analysis was used for testing interaction effects.
Contrast analyses with Tukey HSD correction were performed to compare means and test interactions.
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